Lady Gaga, 'Machete Kills' Clip, Trailer [VIDEOS]: First Look at Action Movie Shows 'Applause' Songstress Taking on Dany Trejo w/ Sexy Clad Sofia Vergara and More

Robert Rodriguez's latest film, Machete Kills (the sequel to Machete), is definitely going to be a crazy thrill ride. An over-the-top first film will clearly lead to an over-the-top sequel, full of sexy ladies, guns, explosions and, of course, Danny Trejo! Now we have a new clip of the anticipated action flick featuring Lady Gaga and Sofia Vergara attempting to stop Machete's armored El Camino car.

Amber Heard, Michelle Rodriguez, Cuba Gooding Jr., Antonio Banderas, Demián Bichir, Alexa Vega, Jessica Alba, Vanessa Hudgens, Edward James Olmos, William Sadler, and Marko Zaror also star.

Here is a synopsis of the film:

In MACHETE KILLS, Danny Trejo returns as ex-Federale agent MACHETE, who is recruited by the President of the United States for a mission which would be impossible for any mortal man - he must take down a madman revolutionary and an eccentric billionaire arms dealer who has hatched a plan to spread war and anarchy across the planet.

Check out this new clip featuring Lady Gaga as well as the film's trailer right here:

Machete Kills opens October 11. 

Gaga is also currently filming her scenes for Sin City 2: a Dame to Kill For. Her co-star, Joseph Gordon-Levitt recently took some time to praise the singer's acting.

"She's a great actress," he said. "And I didn't know that. You know she came in and I was like, 'Okay, sure, they're having a huge pop star do a scene in the movie, I understand,' but then she came in and like, nailed it! She had her character down, and she was like a total pro and did a great job. I was really impressed."